The purpose of the current study was to find out the correlation and cause effect relationship between LDL cholesterol and nephropathy in diabetic
population. Type-2 diabetes mellitus is an increasingly common metabolic abnormality associated with microvascular and macrovascular complications. It is also the most common cause of end stage renal disease (ESRD). Lipoprotein (Lp) is a recently discussed important independent and inheritable risk factor for micro and macrovascular complications and also an independent risk factor for the progression of diabetic nephropathy in DM2 patients with overt proteinuria.