New derivative thiourea and thiocarbamate on oxidation peroxide lipids at adjuvant arthritis at white rat in a clouse. In structure the influence new derivative thiocarbamate and thiourea on peroxide oxidation lipids is investigated at adjuvant arthritis at white rat. Preparation BIK-15 reduce of intensity peroxide lipids and raise of activity enzymes antioxidant of system (SOD, KT) and in this respect they surpass butadione and indometacin.