Silk fibroin (SF) is an excellent raw material for making many useful materials. Fibroin materials can be used in various environments. For this reason, it is very important to know the information about the amount of fibroin swelling in which solution medium and its swelling speed. Therefore, we have conducted preliminary research and studied the properties of swelling of SF fibers obtained from silk fiber waste in different media solutions. The results showed that in the solution with an alkaline medium, the degree of total shrinkage of SF fiber was observed to be relatively high, and the swelling rate was also found to be high.