This article explores the growing interdependence between urbanization and infrastructure development in the context of global and regional urban growth. As cities expand and populations migrate from rural to urban areas, the pressure on transportation systems, housing, sanitation, and energy supply intensifies. Through statistical insights, case studies, and literature reviews, the paper evaluates how modern infrastructure serves as the backbone of sustainable urbanization. It also identifies current challenges and innovative approaches such as smart infrastructure, integrated urban planning, and eco-friendly systems to create livable, inclusive cities.