It has been established that imarant almost halves the antibody titre to ram's erythrocytes in peripheral blood of mice, while under the influence of "fili-saw" and "tribulipil" the antibody titer increases by 1.38-1.50 times. The number of cells in the thymus, bone marrow and lymph nodes decreases by 1.50-1.79 times, and plant remedies raise their level by 1.20-1.41 times.