Although reading comprehension is considered to be one of the substantial skills of English language, it is not always feasible for all learners to acquire the best reading competency. Most English learners claim that they often tend to come across certain problems in comprehending some English texts for one or another reason. This article deals with several difficulties in reading comprehension, which can be exemplified by trouble in decoding, inadequate vocabulary, deficiency of background knowledge as well as cross-cultural obstacles. In addition, this paper aims to clearly explicate how these particular reading difficulties may bring a number of impediments to the progress of each reader, and what kind of solutions to the problems can be proposed.