In this work the synthesis of monoamines on the base of acetylene aminoalcohols and diamines in the presence of acetylene, paraform and secondary amines by the Mannich reaction.was inivestigated. The structure, physico-chemical culconstants and conditions of formation of synthesized monoamines and diamines with high yields have been determined. In the molecules of monoamines and diamines there are chemically active centers: -C ≡ C-, atom –N= and -C ≡ C - H. The reactions halogenation of triple bond by halogenated acids and the formation of a quaternary salts have been studied. The structure of the synthesized products was confirmed by IR and PMR spectrums. Their physico-chemical constants and yields have been determined. Dependence of the products yield on the nature of the used catalysts was determined.