In this article, the grain quality of 21 winter soft wheat varieties at the Khorezm Experimental Station of the Scientific Research Institute of Cereals and Legumes was studied in laboratory experiments. In the soil-climatic conditions of the Khorezm region, it is possible to obtain high-quality grain from winter soft wheat varieties Andijon-2, Jiva, Karavan, Kroshka, MV-Nemere, and Step. Varieties with high grain quality are involved in the breeding program at the Khorezm Experimental Station.