In order to form a taxonomic list of earthworms in the territory of Uzbekistan and its north-western region, a comparative analysis was conducted based on the available data and the results of our research. For the fauna of Uzbekistan, 2 new species belonging to the genus Perelia (Perelia persiana, Perelia turcmenica) and 1 specie belonging to the genus Lumbricus (Lumbricus rubellus) were recorded for the first time. Also, the research results show that 22 identified species were recorded for the first time as new species for the fauna of the north-western region of Uzbekistan.