The reasons for drought and the impact of agricultural drought to crop production in the Khorezm region are the main content of the article. The possibility of using lakes water to find solutions and to be prepared for the problem reviewed. The lakes were divided into 5 groups according to their area. The possible water supply areas for each group of the lakes were determined and indicated by buffer analysis. The agricultural fields within the buffer zone were selected for the cultivation of main food crops through analyzing soil bonitet: wheat, corn, vegetables, and rice. The soil ball bonitet was divided into 100-60, 59-50, 49-40, 39-0 corresponding to the type of crops. It is recommended to use water of the large and medium-sized lakes in drought years and areas with 2966.46 ha for wheat, 2821.09 ha for corn, 2724.93 ha for vegetables, and 2466.84 ha for rice were found useful.