In the article, pulsating fluid flows in tubes with changingwalls,which are of great importance in biological mechanics, in particular, intheflowofblood in the arterial vessel, are investigated. The solution of the problem obtained formulas for the distribution of pressure gradient, velocity and flowrate. Impedancemethod analyzed the increase in hydraulic resistance depending on the frequencyofoscillation.It was found that with large values 2 α of hydraulic resistance gow wth owth 2 α . For crowding out the same flow rates, for small and with large vales of thvibrational number or frequency, the energy input is different. Since forsmall vaes of the oscillatory number, fluctuations in the flow rat of the fluid flutuate in thsame phase with the oscillation of the pressure gradient, and for large vales of th number, the oscillation of the phase of the fluid flow is hifted by 90 degrees than fctuations in the pressure gradient. In addition, for large values of the viratnal number, a tenfold size increases the maximum amplitue of the pressure gradient, relatively, than at low frequencies. This feature leads to an increase in the enrgyost of pumping fluid due to wall oscillation.